Case Definition of Avian Influenza

1. Suspect Case
Called suspect cases if there are symptoms of fever> 38 "C accompanied by at least 1 symptom and a result of virus / history of the following contacts:
A. Flu-like symptoms such as cough, runny nose, headache, sore throat and shortness of breath
B. The result of the virus / history of contacts:
- Inspection results positive for influenza A virus without knowing subtype
- History of contacts 1 week before onset of symptoms with birds that died because of illness
- History of contacts 1 week before onset of symptoms by patients who proved to confirm the laboratory
- Specialized laboratory workers handling samples from persons or animals suspected of being infected Highly Pathogenic Avian Influenza Viruses working in the laboratory 1 week before onset of symptoms

2. Probable Case
Probable cases were suspect cases with positive serologic results indicating the occurrence of specific antibody titer increased by 4 times the normal value

3. Confirmed Cases
The case confirmed when positive results of H5N1 virus culturing or examination results by Rt-PCR positive for H5N1. Or an increase in H5-specific antibody titers greater than 4 times the normal value and the results of the IFA (immunofluorescence antibody) positive for H5 antigen.

4. Case Exposured
Exposured cases are cases that show no clinical symptoms or remain healthy but serologic examination showed positive results.